Phytochemical Screening And Test For Reducing Uric Acid Levels In Male Rats After Administration Of Ethanol Extract Of The Herb Binara (Artemisia vulgaris L.)

Hyperuricemia is a metabolic disease generally characterized by high uric acid levels in the blood. The general treatment strategy for hyperuricemia to decrease production using xanthine oxidation reductase inhibitors such as allopurinol and uricosuric agents. However, drugs showed side effects, including skin rashes, diarrhoea liver damage. To overcome effects of synthetic drugs, alternatives are used, namely researching find plants that have activity reducing levels. likely due presence flavonoid compounds antioxidants. Flavonoids active kaempferol through oxidase inhibitors. Quercetin also has potential reduce inhibition enzyme. Binara plant (Artemisia vulgaris L.) flavonoids, tannins, alkaloids, glycosides saponins which antioxidants analgesics, anti-inflammatory, immunomodulating, hepatoprotective, secondary metabolites terpenes, phenolic acids. Karo people traditionally used leaves treat wounds, heartburn chewing some then placing them on wounds outside body, cuts stomach ulcers around sick stomach. This study was conducted know anti-hyperuricemia effect Ethanol Extract Herba gout rats; phytochemical screening carried out first determine content compounds. results Herb fulfilled simplicia characterization requirements contained glycosides, steroids. been shown rats, with best concentrations being 400 800 mg/kg body weight. based significantly different p>0.05 compared positive control group.